Megaloblastic anemia complicating thalassemia.

Megaloblastic erythropoiesis is known to occur in patients with chronic hemolytic anaemia. It has been described in association with sickle cell anemia (Oliner and Heller 1959 ), thalassaemia (Robinson and Watson 1963 ), congenital spherocytosis ( Delamore et al. 1961), and acquired hemolytic anemia ( Forshaw and Harwood 1963). In a survey of the literature up to 1962, Robinson and Watson (1963) recorded 16 cases and added one of their own. The youngest patient in their review was 11 89 years old, and there appears to be a paucity of reports in the younger age groups. The object of this communication is to report two cases of megaloblastic anemia complicating thalassaemia in infants. The object of this communication is to report two cases of megaloblastic anemia complicating thalassaemia in infants.